Pyridoxal phosphatase

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PHOSPHO2

← Previous revision Revision as of 08:21, 9 July 2025
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:pyridoxal 5′-phosphate + H<sub>2</sub>O <math>\rightleftharpoons</math> pyridoxal + phosphate
:pyridoxal 5′-phosphate + H<sub>2</sub>O <math>\rightleftharpoons</math> pyridoxal + phosphate


It also acts on pyridoxine phosphate (PNP), pyridoxamine phosphate (PMP), 4-pyridoxic acid phosphate and 4-deoxypyridoxine phosphate to remove their phosphate groups.
It also acts on pyridoxine phosphate (PNP), pyridoxamine phosphate (PMP), 4-pyridoxic acid phosphate and 4-deoxypyridoxine phosphate to remove their phosphate groups. Two human genes produce proteins that act as this kind of enzyme: ''[[PDXP]]'' and ''[[PHOSPHO2]]''.


This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on phosphoric [[ester|monoester]] bonds. The [[List of enzymes|systematic name]] is '''pyridoxal-5′-phosphate phosphohydrolase'''. Other names in common use include '''vitamine B<sub>6</sub> (pyridoxine) phosphatase''', '''PLP phosphatase''', '''vitamin B<sub>6</sub>-phosphate phosphatase''', and '''PNP phosphatase'''. This enzyme participates in vitamin B<sub>6</sub> metabolism.
This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on phosphoric [[ester|monoester]] bonds. The [[List of enzymes|systematic name]] is '''pyridoxal-5′-phosphate phosphohydrolase'''. Other names in common use include '''vitamine B<sub>6</sub> (pyridoxine) phosphatase''', '''PLP phosphatase''', '''vitamin B<sub>6</sub>-phosphate phosphatase''', and '''PNP phosphatase'''. This enzyme participates in vitamin B<sub>6</sub> metabolism.
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